Kalender next 42tg

Keine Termine

Event Kalender

März 2024
Mo Di Mi Do Fr Sa So
26 27 28 29 1 2 3
4 5 6 7 8 9 10
11 12 13 14 15 16 17
18 19 20 21 22 23 24
25 26 27 28 29 30 31

Banners

Propolis Prevents Hepatorenal Injury Induced by Chronic Exposure to Carbon Tetrachloride
Evid Based Complement Alternat Med[1], 2012;2012:235358. Epub 2011 Aug 4

Carbon tetrachloride (CCl(4)) is a well-known hepatotoxicant, and its exposure induces hepatorenal injury via oxidative stress and biochemical alterations. This study had been conducted to confirm the protective role of propolis extract on CCl(4)-induced hepatorenal oxidative stress and resultant injury.

Propolis extracts collected from Gwalior district and 24 female Sprague Dawley rats were used for experiment. Animals were exposed to CCl(4) (0.15 mL/kg, i.p.) for 12 weeks (5 days/week) followed by treatment with propolis extract (200 mg/kg, p.o.) for consecutive 2 weeks. CCl(4) exposure significantly depleted blood sugar and hemoglobin level and raised the level of transaminases, alkaline phosphatase, lactate dehydrogenase, protein, urea, albumin, bilirubin, creatinine, triglycerides, and cholesterol in serum. Lipid peroxidation was enhanced, whereas GSH was decreased significantly in liver and kidney in CCl(4)-intoxicated group.

Ethanolic extract of propolis successfully prevented these alterations in experimental animals. Activities of catalase, adenosine triphosphatase, glucose-6-phosphatase, acid, and alkaline phosphatase were also maintained towards normal with propolis therapy. Light microscopical studies showed considerable protection in liver and kidney with propolis treatment, thus, substantiated biochemical observations.

This study confirmed hepatoprotective potential of propolis extract against chronic injury induced by CCl(4) by regulating antioxidative defense activities.

References

  1. ^ Evid Based Complement Alternat Med (www.hindawi.com)

Apitherapy News

Attachments:
FileDescriptionFile sizeDownloads
Download this file (HINDAWI_2011_08_16.pdf)HINDAWI_2011_08_16.pdfHindawi4862 kB2854

Phänologie

Agroscope - Imkerei
Das Zentrum für Bienenforschung ist Bestandteil der Forschungsanstalt  Agroscope Liebefeld-Posieu…
VSI - Verband Schwei…
VSI - Verband Schweizerischer Imkergerätehersteller und Imkereifachgeschäfte
More Links » JoelLipman.Com

aktualisierte Beiträge

Wetter

who is online

Aktuell sind 514 Gäste, 24 Bots und keine Mitglieder online


24 Bots:
12 x AhrefsBot
6 x SemrushBot
4 x Googlebot
1 x DotBot
1 x bingbot